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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIRAP
All Species:
10
Human Site:
S75
Identified Species:
27.5
UniProt:
P58753
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58753
NP_001034750.1
221
23883
S75
S
L
P
P
T
H
A
S
D
S
G
S
S
R
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001123907
220
24019
S74
S
L
P
P
T
H
A
S
D
S
G
S
S
R
W
Dog
Lupus familis
XP_851910
435
46698
S289
T
Y
V
G
A
S
S
S
S
G
S
S
G
R
W
Cat
Felis silvestris
Mouse
Mus musculus
Q99JY1
241
26017
S95
P
P
T
H
V
D
S
S
S
S
S
S
G
R
W
Rat
Rattus norvegicus
XP_001055833
250
26813
S104
P
T
H
V
D
S
S
S
S
S
S
S
G
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514911
373
39387
H145
P
S
S
E
S
R
A
H
A
A
G
G
G
D
G
Chicken
Gallus gallus
NP_001020000
221
24806
V80
R
W
V
K
S
Y
D
V
C
I
C
H
S
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922965
226
25971
H78
K
Y
D
L
Y
L
C
H
S
E
K
D
M
E
Q
Tiger Blowfish
Takifugu rubipres
NP_001106667
180
20118
A40
P
Q
S
V
V
G
S
A
L
S
C
A
R
K
Y
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.2
42.7
N.A.
73.4
70.8
N.A.
35.9
45.7
N.A.
38
34.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
95.9
46.9
N.A.
78.8
76.8
N.A.
45.3
59.7
N.A.
53.9
44.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
26.6
N.A.
33.3
33.3
N.A.
13.3
6.6
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
40
N.A.
40
40
N.A.
26.6
20
N.A.
0
40
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
34
12
12
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
12
0
23
0
0
0
0
% C
% Asp:
0
0
12
0
12
12
12
0
23
0
0
12
0
12
0
% D
% Glu:
0
0
0
12
0
0
0
0
0
12
0
0
0
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
12
0
0
0
12
34
12
45
0
12
% G
% His:
0
0
12
12
0
23
0
23
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
12
0
0
12
0
0
0
0
0
0
12
0
0
12
0
% K
% Leu:
0
23
0
12
0
12
0
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
45
12
23
23
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
12
0
0
0
0
12
0
0
0
0
0
0
12
56
0
% R
% Ser:
23
12
23
0
23
23
45
56
45
56
34
56
34
0
0
% S
% Thr:
12
12
12
0
23
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
23
23
23
0
0
12
0
0
0
0
0
0
12
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
56
% W
% Tyr:
0
23
0
0
12
12
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _